Publication: Dopamine D2/3- and μ-opioid receptor antagonists reduce cue-induced responding and reward impulsivity in humans
Dopamine D2/3- and μ-opioid receptor antagonists reduce cue-induced responding and reward impulsivity in humans
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Weber, S. C., Beck-Schimmer, B., Kajdi, M.-E., Müller, D., Tobler, P. N., & Quednow, B. B. (2016). Dopamine D2/3- and μ-opioid receptor antagonists reduce cue-induced responding and reward impulsivity in humans. Translational Psychiatry, 6, e850. https://doi.org/10.1038/tp.2016.113
Abstract
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Increased responding to drug-associated stimuli (cue reactivity) and an inability to tolerate delayed gratification (reward impulsivity) have been implicated in the development and maintenance of drug addiction. Whereas data from animal studies suggest that both the dopamine and opioid system are involved in these two reward-related processes, their role in humans is less clear. Moreover, dopaminergic and opioidergic drugs have not been directly compared with regard to these functions, even though a deeper understanding of the underly
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- Weber, S C
- Beck-Schimmer, B
- Kajdi, M-E
- Müller, D
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Citations
Weber, S. C., Beck-Schimmer, B., Kajdi, M.-E., Müller, D., Tobler, P. N., & Quednow, B. B. (2016). Dopamine D2/3- and μ-opioid receptor antagonists reduce cue-induced responding and reward impulsivity in humans. Translational Psychiatry, 6, e850. https://doi.org/10.1038/tp.2016.113
