Publication: A genome-wide RNAi screen for genes important for proliferation of cultured Drosophila cells at low temperature identifies the Ball/VRK protein kinase
A genome-wide RNAi screen for genes important for proliferation of cultured Drosophila cells at low temperature identifies the Ball/VRK protein kinase
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Mendaluk, A., Caussinus, E., Boutros, M., & Lehner, C. F. (2023). A genome-wide RNAi screen for genes important for proliferation of cultured Drosophila cells at low temperature identifies the Ball/VRK protein kinase. Chromosoma, 132(1), 31–53. https://doi.org/10.1007/s00412-023-00787-6
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A change in ambient temperature is predicted to disrupt cellular homeostasis by affecting all cellular processes in an albeit non-uniform manner. Diffusion is generally less temperature-sensitive than enzymes, for example, and each enzyme has a characteristic individual temperature profile. The actual effects of temperature variation on cells are still poorly understood at the molecular level. Towards an improved understanding, we have performed a genome-wide RNA interference screen with S2R + cells. This Drosophila cell line prolifer
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- Mendaluk, Anna
- Caussinus, Emmanuel
- Boutros, Michael
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Mendaluk, A., Caussinus, E., Boutros, M., & Lehner, C. F. (2023). A genome-wide RNAi screen for genes important for proliferation of cultured Drosophila cells at low temperature identifies the Ball/VRK protein kinase. Chromosoma, 132(1), 31–53. https://doi.org/10.1007/s00412-023-00787-6
