Publication:

Early life adversities are associated with lower expected value signaling in the adult brain

Date

Date

Date
2024
Journal Article
Published version

Citations

Citation copied

Sacu, S., Dubois, M., Hezemans, F. H., Aggensteiner, P.-M., Monninger, M., Brandeis, D., Banaschewski, T., Hauser, T. U., & Holz, N. E. (2024). Early life adversities are associated with lower expected value signaling in the adult brain. Biological Psychiatry, 96(12), 948–958. https://doi.org/10.1016/j.biopsych.2024.04.005

Abstract

Abstract

Abstract

Background: Early adverse experiences are assumed to affect fundamental processes of reward learning and decision making. However, computational neuroimaging studies investigating these circuits in the context of adversity are sparse and limited to studies conducted in adolescent samples, leaving the long-term effects unexplored.

Methods: Using data from a longitudinal birth cohort study (n = 156; 87 female), we investigated associations between adversities and computational markers of reward learning (i.e., expected value, predictio

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8 since deposited on 2024-07-25
Acq. date: 2025-11-12

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46 since deposited on 2024-07-25
Acq. date: 2025-11-12

Additional indexing

Creators (Authors)

  • Sacu, Seda
    affiliation.icon.alt
  • Dubois, Magda
    affiliation.icon.alt
  • Hezemans, Frank H
    affiliation.icon.alt
  • Aggensteiner, Pascal-M
    affiliation.icon.alt
  • Monninger, Maximilian
    affiliation.icon.alt
  • Brandeis, Daniel
    affiliation.icon.alt
  • Banaschewski, Tobias
    affiliation.icon.alt
  • Hauser, Tobias U
    affiliation.icon.alt
  • Holz, Nathalie E
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
96

Number

Number

Number
12

Page range/Item number

Page range/Item number

Page range/Item number
948

Page end

Page end

Page end
958

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Keywords

Adverse experiences, Early-life stress, Expected value, Prediction error, Reinforcement learning, fMRI

Language

Language

Language
English

Publication date

Publication date

Publication date
2024-12-01

Date available

Date available

Date available
2024-07-25

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
0006-3223

OA Status

OA Status

OA Status
Hybrid

Free Access at

Free Access at

Free Access at
DOI

PubMed ID

PubMed ID

PubMed ID

Metrics

Downloads

8 since deposited on 2024-07-25
Acq. date: 2025-11-12

Views

46 since deposited on 2024-07-25
Acq. date: 2025-11-12

Citations

Citation copied

Sacu, S., Dubois, M., Hezemans, F. H., Aggensteiner, P.-M., Monninger, M., Brandeis, D., Banaschewski, T., Hauser, T. U., & Holz, N. E. (2024). Early life adversities are associated with lower expected value signaling in the adult brain. Biological Psychiatry, 96(12), 948–958. https://doi.org/10.1016/j.biopsych.2024.04.005

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