Publication: Studying the morphology, composition and function of the photoreceptor primary cilium in zebrafish
Studying the morphology, composition and function of the photoreceptor primary cilium in zebrafish
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Masek, M., Zang, J., Mateos, J. M., Garbelli, M., Ziegler, U., Neuhauss, S. C. F., & Bachmann-Gagescu, R. (2023). Studying the morphology, composition and function of the photoreceptor primary cilium in zebrafish. Methods in Cell Biology, 175, 97–128. https://doi.org/10.1016/bs.mcb.2022.10.004
Abstract
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Vision is one of our dominant senses and its loss has a profound impact on the life quality of affected individuals. Highly specialized neurons in the retina called photoreceptors convert photons into neuronal responses. This conversion of photons is mediated by light sensitive opsin proteins, which are found in the outer segments of the photoreceptors. These outer segments are highly specialized primary cilia, explaining why retinal dystrophy is a key feature of ciliopathies, a group of diseases resulting from abnormal and dysfunctio
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- Masek, Markus
- Garbelli, Marco
- Ziegler, Urs
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Masek, M., Zang, J., Mateos, J. M., Garbelli, M., Ziegler, U., Neuhauss, S. C. F., & Bachmann-Gagescu, R. (2023). Studying the morphology, composition and function of the photoreceptor primary cilium in zebrafish. Methods in Cell Biology, 175, 97–128. https://doi.org/10.1016/bs.mcb.2022.10.004