Publication: Bone morphogenetic protein-2 enhances bone formation when delivered by a synthetic matrix containing hydroxyapatite/tricalciumphosphate
Bone morphogenetic protein-2 enhances bone formation when delivered by a synthetic matrix containing hydroxyapatite/tricalciumphosphate
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Jung, R. E., Weber, F. E., Thoma, D. S., Ehrbar, M., Cochran, D. L., & Hämmerle, C. H. F. (2008). Bone morphogenetic protein-2 enhances bone formation when delivered by a synthetic matrix containing hydroxyapatite/tricalciumphosphate. Clinical Oral Implants Research, 19(2), 188–195. https://doi.org/10.1111/j.1600-0501.2007.01431.x
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PURPOSE: The aim of the present study was to test whether or not a synthetic matrix consisting of a polyethylene glycol (PEG) hydrogel containing recombinant human bone morphogenetic protein-2 (rhBMP-2) combined with grafting materials enhances bone regeneration compared with grafting alone or empty control sites. MATERIAL AND METHODS: In each of 10 rabbits, four titanium cylinders were screwed in perforated slits made in the external cortical bones of the calvaria. The following four treatment modalities were randomly allocated: (1)
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Jung, R. E., Weber, F. E., Thoma, D. S., Ehrbar, M., Cochran, D. L., & Hämmerle, C. H. F. (2008). Bone morphogenetic protein-2 enhances bone formation when delivered by a synthetic matrix containing hydroxyapatite/tricalciumphosphate. Clinical Oral Implants Research, 19(2), 188–195. https://doi.org/10.1111/j.1600-0501.2007.01431.x