Publication: Internal consistency and compatibility of the 3Rs and 3Vs principles for project evaluation of animal research
Internal consistency and compatibility of the 3Rs and 3Vs principles for project evaluation of animal research
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Eggel, M., & Würbel, H. (2021). Internal consistency and compatibility of the 3Rs and 3Vs principles for project evaluation of animal research. Laboratory Animals, 55(3), 233–243. https://doi.org/10.1177/0023677220968583
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Using animals for research raises ethical concerns that are addressed in project evaluation by weighing expected harm to animals against expected benefit to society. A harm-benefit analysis (HBA) relies on two preconditions: (a) the study protocol is scientifically suitable and (b) the use of (sentient) animals and harm imposed on them are necessary for achieving the study's aims. The 3Rs (Replace, Reduce and Refine) provide a guiding principle for evaluating whether the use of animals, their number and the harm imposed on them are ne
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Eggel, M., & Würbel, H. (2021). Internal consistency and compatibility of the 3Rs and 3Vs principles for project evaluation of animal research. Laboratory Animals, 55(3), 233–243. https://doi.org/10.1177/0023677220968583