Publication: A Comprehensive Review on the Role of Non-Coding RNAs in the Pathophysiology of Bipolar Disorder
A Comprehensive Review on the Role of Non-Coding RNAs in the Pathophysiology of Bipolar Disorder
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Ghafouri-Fard, S., Badrlou, E., Taheri, M., Dürsteler, K. M., Brühl, A. B., Sadeghi-Bahmani, D., & Brand, S. (2021). A Comprehensive Review on the Role of Non-Coding RNAs in the Pathophysiology of Bipolar Disorder. International Journal of Molecular Sciences, 22(10), 5156. https://doi.org/10.3390/ijms22105156
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Aim: Bipolar disorder is a multifactorial disorder being linked with dysregulation of several genes. Among the recently acknowledged factors in the pathophysiology of bipolar disorder are non-coding RNAs (ncRNAs).
Methods: We searched PubMed and Google Scholar databases to find studies that assessed the expression profile of miRNAs, lncRNAs and circRNAs in bipolar disorder.
Results: Dysregulated ncRNAs in bipolar patients have been enriched in several neuron-related pathways such as GABAergic and glutamatergic synapses, morphine add
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Ghafouri-Fard, S., Badrlou, E., Taheri, M., Dürsteler, K. M., Brühl, A. B., Sadeghi-Bahmani, D., & Brand, S. (2021). A Comprehensive Review on the Role of Non-Coding RNAs in the Pathophysiology of Bipolar Disorder. International Journal of Molecular Sciences, 22(10), 5156. https://doi.org/10.3390/ijms22105156