Publication: Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium
Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium
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Constantinides, C., Han, L. K. M., Alloza, C., Antonucci, L. A., Arango, C., Ayesa-Arriola, R., Banaj, N., Bertolino, A., Borgwardt, S., Bruggemann, J., Bustillo, J., Bykhovski, O., Calhoun, V., Carr, V., Catts, S., Chung, Y.-C., Crespo-Facorro, B., Díaz-Caneja, C. M., Donohoe, G., … et al. (2023). Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium. Molecular Psychiatry, 28, 1201–1209. https://doi.org/10.1038/s41380-022-01897-w
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Abstract
Schizophrenia (SZ) is associated with an increased risk of life-long cognitive impairments, age-related chronic disease, and premature mortality. We investigated evidence for advanced brain ageing in adult SZ patients, and whether this was associated with clinical characteristics in a prospective meta-analytic study conducted by the ENIGMA Schizophrenia Working Group. The study included data from 26 cohorts worldwide, with a total of 2803 SZ patients (mean age 34.2 years; range 18-72 years; 67% male) and 2598 healthy controls (mean ag
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- Constantinides, Constantinos
- Han, Laura K M
- Alloza, Clara
- Antonucci, Linda Antonella
- Arango, Celso
- Ayesa-Arriola, Rosa
- Banaj, Nerisa
- Bertolino, Alessandro
- Borgwardt, Stefan
- Bruggemann, Jason
- Bustillo, Juan
- Bykhovski, Oleg
- Calhoun, Vince
- Carr, Vaughan
- Catts, Stanley
- Chung, Young-Chul
- Crespo-Facorro, Benedicto
- Díaz-Caneja, Covadonga M
- Donohoe, Gary
- Plessis, Stefan Du
- Edmond, Jesse
- Ehrlich, Stefan
- Emsley, Robin
- Eyler, Lisa T
- Fuentes-Claramonte, Paola
- Georgiadis, Foivos
- Green, Melissa
- Guerrero-Pedraza, Amalia
- Ha, Minji
- Hahn, Tim
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Constantinides, C., Han, L. K. M., Alloza, C., Antonucci, L. A., Arango, C., Ayesa-Arriola, R., Banaj, N., Bertolino, A., Borgwardt, S., Bruggemann, J., Bustillo, J., Bykhovski, O., Calhoun, V., Carr, V., Catts, S., Chung, Y.-C., Crespo-Facorro, B., Díaz-Caneja, C. M., Donohoe, G., … et al. (2023). Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium. Molecular Psychiatry, 28, 1201–1209. https://doi.org/10.1038/s41380-022-01897-w
