Publication: Head/neck paragangliomas: focus on tumor location, mutational status and plasma methoxytyramine
Head/neck paragangliomas: focus on tumor location, mutational status and plasma methoxytyramine
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Richter, S., Qiu, B., Ghering, M., Kunath, C., Constantinescu, G., Luths, C., Pamporaki, C., Bechmann, N., Meuter, L., Kwapiszewska, A., Deutschbein, T., Nölting, S., Peitzsch, M., Robledo, M., Prejbisz, A., Pacak, K., Gudziol, V., Timmers, H. J. L. M., & Eisenhofer, G. (2022). Head/neck paragangliomas: focus on tumor location, mutational status and plasma methoxytyramine. Endocrine-Related Cancer, 29(4), 213–224. https://doi.org/10.1530/ERC-21-0359
Abstract
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Abstract
Head and neck paragangliomas (HNPGLs) are tumors of parasympathetic origin that occur at variable locations and are often secondary to germline mutations in succinate dehydrogenase (SDH) subunit genes. Occasionally, these tumors produce catecholamines. Here, we assessed whether different locations of HNPGLs relate to the presence of SDHx mutations, catecholamine production and other presentations. In this multicenter study, we collected clinical and biochemical data from 244 patients with HNPGLs and 71 patients without HNPGLs. We clar
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Creators (Authors)
- Richter, Susan
- Qiu, Bei
- Ghering, Mirthe
- Kunath, Carola
- Constantinescu, Georgiana
- Luths, Charlotte
- Pamporaki, Christina
- Bechmann, Nicole
- Meuter, Leah
- Kwapiszewska, Aleksandra
- Deutschbein, Timo
- Nölting, Svenja
- Peitzsch, Mirko
- Robledo, Mercedes
- Prejbisz, Aleksander
- Pacak, Karel
- Gudziol, Volker
- Timmers, Henri J L M
- Eisenhofer, Graeme
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Richter, S., Qiu, B., Ghering, M., Kunath, C., Constantinescu, G., Luths, C., Pamporaki, C., Bechmann, N., Meuter, L., Kwapiszewska, A., Deutschbein, T., Nölting, S., Peitzsch, M., Robledo, M., Prejbisz, A., Pacak, K., Gudziol, V., Timmers, H. J. L. M., & Eisenhofer, G. (2022). Head/neck paragangliomas: focus on tumor location, mutational status and plasma methoxytyramine. Endocrine-Related Cancer, 29(4), 213–224. https://doi.org/10.1530/ERC-21-0359
