Publication:
Dysregulated Expression of Arterial MicroRNAs and Their Target Gene Networks in Temporal Arteries of Treatment-Naïve Patients with Giant Cell Arteritis

Date

Date

Date
2021
Journal Article
Published version

Abstract

Abstract

Abstract
In this study, we explored expression of microRNA (miR), miR-target genes and matrix remodelling molecules in temporal artery biopsies (TABs) from treatment-naïve patients with giant cell arteritis (GCA, n = 41) and integrated these analyses with clinical, laboratory, ultrasound and histological manifestations of GCA. NonGCA patients (n = 4) served as controls. GCA TABs exhibited deregulated expression of several miRs (miR-21-5p, -145-5p, -146a-5p, -146b-5p, -155-5p, 424-3p, -424-5p, -503-5p), putative miR-target genes (YAP1, PELI1, F

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51 since deposited on 2021-07-14
46last week
Acq. date: 2025-11-13

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69 since deposited on 2021-07-14
68last week
Acq. date: 2025-11-13

Additional indexing

Creators (Authors)

  • Kuret, Tadeja
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  • Lakota, Katja
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  • Čučnik, Saša
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  • Jurčič, Vesna
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  • Distler, Oliver
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  • Rotar, Žiga
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  • Hočevar, Alojzija
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  • Sodin-Šemrl, Snežna
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  • Frank-Bertoncelj, Mojca
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Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
22

Number

Number

Number
12

Page range/Item number

Page range/Item number

Page range/Item number
6520

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2021-06-17

Date available

Date available

Date available
2021-07-14

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
1422-0067

OA Status

OA Status

OA Status
Gold

Free Access at

Free Access at

Free Access at
Pubmed ID

PubMed ID

PubMed ID

PubMed ID

Metrics

Downloads

51 since deposited on 2021-07-14
46last week
Acq. date: 2025-11-13

Views

69 since deposited on 2021-07-14
68last week
Acq. date: 2025-11-13
Gold Open Access
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