Publication: Dysregulated Expression of Arterial MicroRNAs and Their Target Gene Networks in Temporal Arteries of Treatment-Naïve Patients with Giant Cell Arteritis
Date
Date
Date
2021
Journal Article
Published version
Abstract
Abstract
Abstract
In this study, we explored expression of microRNA (miR), miR-target genes and matrix remodelling molecules in temporal artery biopsies (TABs) from treatment-naïve patients with giant cell arteritis (GCA, n = 41) and integrated these analyses with clinical, laboratory, ultrasound and histological manifestations of GCA. NonGCA patients (n = 4) served as controls. GCA TABs exhibited deregulated expression of several miRs (miR-21-5p, -145-5p, -146a-5p, -146b-5p, -155-5p, 424-3p, -424-5p, -503-5p), putative miR-target genes (YAP1, PELI1, F
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51 since deposited on 2021-07-14
46last week
Acq. date: 2025-11-13
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69 since deposited on 2021-07-14
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Acq. date: 2025-11-13
Additional indexing
Creators (Authors)
Journal/Series Title
Journal/Series Title
Journal/Series Title
Volume
Volume
Volume
22
Number
Number
Number
12
Page range/Item number
Page range/Item number
Page range/Item number
6520
Item Type
Item Type
Item Type
Journal Article
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
English
Publication date
Publication date
Publication date
2021-06-17
Date available
Date available
Date available
2021-07-14
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
1422-0067
OA Status
OA Status
OA Status
Gold
Free Access at
Free Access at
Free Access at
Pubmed ID
Publisher DOI
Metrics
Downloads
51 since deposited on 2021-07-14
46last week
Acq. date: 2025-11-13
Views
69 since deposited on 2021-07-14
68last week
Acq. date: 2025-11-13
Gold Open Access
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