Publication: Differential role of GABAA receptors and neuroligin 2 for perisomatic GABAergic synapse formation in the hippocampus
Differential role of GABAA receptors and neuroligin 2 for perisomatic GABAergic synapse formation in the hippocampus
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Panzanelli, P., Früh, S., & Fritschy, J.-M. (2017). Differential role of GABAA receptors and neuroligin 2 for perisomatic GABAergic synapse formation in the hippocampus. Brain Structure & Function, 222(9), 4149–4161. https://doi.org/10.1007/s00429-017-1462-7
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Perisomatic GABAergic synapses onto hippocampal pyramidal cells arise from two populations of basket cells with different neurochemical and functional properties. The presence of the dystrophin-glycoprotein complex in their postsynaptic density (PSD) distinguishes perisomatic synapses from GABAergic synapses on dendrites and the axon-initial segment. Targeted deletion of neuroligin 2 (NL2), a transmembrane protein interacting with presynaptic neurexin, has been reported to disrupt postsynaptic clustering of GABAA receptors (GABAAR) an
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- Panzanelli, Patrizia
- Früh, Simon
- Fritschy, Jean-Marc
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Panzanelli, P., Früh, S., & Fritschy, J.-M. (2017). Differential role of GABAA receptors and neuroligin 2 for perisomatic GABAergic synapse formation in the hippocampus. Brain Structure & Function, 222(9), 4149–4161. https://doi.org/10.1007/s00429-017-1462-7
