Publication: Measuring Circadian Rhythms in Human Cells
Measuring Circadian Rhythms in Human Cells
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Du, N.-H., & Brown, S. A. (2021). Measuring Circadian Rhythms in Human Cells. In S. A. Brown (Ed.), Circadian Clocks : Methods and Protocols (No. 2130; Issue 2130, pp. 53–67). Springer. https://doi.org/10.1007/978-1-0716-0381-9_4
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Human cells, especially primary fibroblasts from skin punch biopsy, have emerged over the last decade as powerful, unlimited, and easily accessible resources that bridge the gap between animal models and human subjects in basic as well as clinical research. The cells also retain molecular circadian clocks that reflect subject-specific differences in circadian physiology, and the cellular rhythms can be measured easily in large scale. This is a series of protocols that describes the procedure to measure circadian rhythms in these cells
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Du, N.-H., & Brown, S. A. (2021). Measuring Circadian Rhythms in Human Cells. In S. A. Brown (Ed.), Circadian Clocks : Methods and Protocols (No. 2130; Issue 2130, pp. 53–67). Springer. https://doi.org/10.1007/978-1-0716-0381-9_4