Publication: Whole blood methylome-derived features to discriminate endocrine hypertension
Whole blood methylome-derived features to discriminate endocrine hypertension
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Armignacco, R., Reel, P. S., Reel, S., et al, & Beuschlein, F. (2022). Whole blood methylome-derived features to discriminate endocrine hypertension. Clinical Epigenetics, 14(1), 142. https://doi.org/10.1186/s13148-022-01347-y
Abstract
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BACKGROUND
Arterial hypertension represents a worldwide health burden and a major risk factor for cardiovascular morbidity and mortality. Hypertension can be primary (primary hypertension, PHT), or secondary to endocrine disorders (endocrine hypertension, EHT), such as Cushing's syndrome (CS), primary aldosteronism (PA), and pheochromocytoma/paraganglioma (PPGL). Diagnosis of EHT is currently based on hormone assays. Efficient detection remains challenging, but is crucial to properly orientate patients for diagnostic confirmation and
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- Armignacco, Roberta
- Reel, Parminder S
- Reel, Smarti
- Beuschlein, Felix
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Armignacco, R., Reel, P. S., Reel, S., et al, & Beuschlein, F. (2022). Whole blood methylome-derived features to discriminate endocrine hypertension. Clinical Epigenetics, 14(1), 142. https://doi.org/10.1186/s13148-022-01347-y
