Publication: The surface-associated exopolysaccharide of bifidobacterium longum 35624 plays an essential role in dampening host proinflammatory responses and repressing local TH17 responses
The surface-associated exopolysaccharide of bifidobacterium longum 35624 plays an essential role in dampening host proinflammatory responses and repressing local TH17 responses
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Schiavi, E., Gleinser, M., Molloy, E., Groeger, D., Frei, R., Ferstl, R., Rodriguez-Perez, N., Ziegler, M., Grant, R., Moriarty, T. F., Plattner, S., Healy, S., O’Connell Motherway, M., Akdis, C. A., Roper, J., Altmann, F., van Sinderen, D., & O’Mahony, L. (2016). The surface-associated exopolysaccharide of bifidobacterium longum 35624 plays an essential role in dampening host proinflammatory responses and repressing local TH17 responses. Applied and Environmental Microbiology, 82, 7185–7196. https://doi.org/10.1128/AEM.02238-16
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Abstract
The immune-modulating properties of certain bifidobacterial strains, such as Bifidobacterium longum subsp. longum 35624 (B. longum 35624), have been well described, although the strain-specific molecular characteristics associated with such immune-regulatory activity are not well defined. It has previously been demonstrated that B. longum 35624 produces a cell surface exopolysaccharide (sEPS), and in this study, we investigated the role played by this exopolysaccharide in influencing the host immune response. B. longum 35624 induced r
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Creators (Authors)
- Schiavi, Elisa
- Gleinser, Marita
- Molloy, Evelyn
- Groeger, David
- Frei, Remo
- Ferstl, Ruth
- Rodriguez-Perez, Noelia
- Ziegler, Mario
- Grant, Ray
- Moriarty, Thomas Fintan
- Plattner, Stephan
- Healy, Selena
- O'Connell Motherway, Mary
- Akdis, Cezmi A
- Roper, Jennifer
- Altmann, Friedrich
- van Sinderen, Douwe
- O'Mahony, Liam
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Schiavi, E., Gleinser, M., Molloy, E., Groeger, D., Frei, R., Ferstl, R., Rodriguez-Perez, N., Ziegler, M., Grant, R., Moriarty, T. F., Plattner, S., Healy, S., O’Connell Motherway, M., Akdis, C. A., Roper, J., Altmann, F., van Sinderen, D., & O’Mahony, L. (2016). The surface-associated exopolysaccharide of bifidobacterium longum 35624 plays an essential role in dampening host proinflammatory responses and repressing local TH17 responses. Applied and Environmental Microbiology, 82, 7185–7196. https://doi.org/10.1128/AEM.02238-16
