Publication: Intestinal IMINO transporter SIT1 is not expressed in human newborns
Intestinal IMINO transporter SIT1 is not expressed in human newborns
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Meier, C., Camargo, S. M., Hunziker, S., Moehrlen, U., Gros, S. J., Bode, P., Leu, S., Meuli, M., Holland-Cunz, S., Verrey, F., & Vuille-Dit-Bille, R. N. (2018). Intestinal IMINO transporter SIT1 is not expressed in human newborns. American Journal Of Physiology. Gastrointestinal And Liver Physiology, 315(5), G887–G895. https://doi.org/10.1152/ajpgi.00318.2017
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The expression of amino acid transporters in small intestine epithelium of human newborns has not been studied yet. It is further not known whether the maturation of imino acid (proline) transport is delayed as in kidney proximal tubule. The possibility to obtain small intestinal tissue from patients undergoing surgery for jejunal or ileal atresia during their first days after birth was used to address these questions. As control, adult terminal ileum tissue was sampled during routine endoscopies. Gene expression of luminal imino- and
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Meier, C., Camargo, S. M., Hunziker, S., Moehrlen, U., Gros, S. J., Bode, P., Leu, S., Meuli, M., Holland-Cunz, S., Verrey, F., & Vuille-Dit-Bille, R. N. (2018). Intestinal IMINO transporter SIT1 is not expressed in human newborns. American Journal Of Physiology. Gastrointestinal And Liver Physiology, 315(5), G887–G895. https://doi.org/10.1152/ajpgi.00318.2017