Publication: A Drosophila RNA helicase gene, pitchoune, is required for cell growth and proliferation and is a potential target of d-Myc.
A Drosophila RNA helicase gene, pitchoune, is required for cell growth and proliferation and is a potential target of d-Myc.
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Zaffran, S., Chartier, A., Gallant, P., Astier, M., Arquier, N., Doherty, D., Gratecos, D., & Sémériva, M. (1998). A Drosophila RNA helicase gene, pitchoune, is required for cell growth and proliferation and is a potential target of d-Myc. Development, 125(18), 3571–3584.
Abstract
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This article describes the characterization of a new Drosophila gene that we have called pitchoune (pit) (meaning small in Provence) because mutations in this gene produce larvae that cannot grow beyond the first instar larval stage although they can live as long as 7-10 days. All the tissues are equally affected and the perfectly shaped larvae are indistinguishable from first instar wild-type animals. Analysis of mutant somatic clones suggests a function in cell growth and proliferation, which is supported by the fact that cell proli
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- Zaffran, S
- Chartier, A
- Gallant, P
- Astier, M
- Arquier, N
- Doherty, D
- Gratecos, D
- Sémériva, M
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Zaffran, S., Chartier, A., Gallant, P., Astier, M., Arquier, N., Doherty, D., Gratecos, D., & Sémériva, M. (1998). A Drosophila RNA helicase gene, pitchoune, is required for cell growth and proliferation and is a potential target of d-Myc. Development, 125(18), 3571–3584.
