Publication: Silk fibroin/hyaluronan scaffolds for human mesenchymal stem cell culture in tissue engineering
Silk fibroin/hyaluronan scaffolds for human mesenchymal stem cell culture in tissue engineering
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Garcia-Fuentes, M., Meinel, A. J., Hilbe, M., Meinel, L., & Merkle, H. P. (2009). Silk fibroin/hyaluronan scaffolds for human mesenchymal stem cell culture in tissue engineering. Biomaterials, 30(28), 5068–5076. https://doi.org/10.1016/j.biomaterials.2009.06.008
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The design of new bioactive scaffolds mimicking the physiologic environment present during tissue formation is an important frontier in biomaterials research. Herein, we evaluated scaffolds prepared from blends of two biopolymers: silk fibroin and hyaluronan. Our rationale was that such blends would allow the combination of silk fibroin's superior mechanical properties with the biological characteristics of hyaluronan. We prepared scaffolds with porous microstructures by freeze-drying aqueous solutions of silk fibroin and hyaluronan a
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Garcia-Fuentes, M., Meinel, A. J., Hilbe, M., Meinel, L., & Merkle, H. P. (2009). Silk fibroin/hyaluronan scaffolds for human mesenchymal stem cell culture in tissue engineering. Biomaterials, 30(28), 5068–5076. https://doi.org/10.1016/j.biomaterials.2009.06.008