Publication:

Developmental origin of patchy axonal connectivity in the neocortex: A computational model

Date

Date

Date
2014
Journal Article
Published version

Citations

Citation copied

Bauer, R., Zubler, F., Hauri, A., Muir, D. R., & Douglas, R. J. (2014). Developmental origin of patchy axonal connectivity in the neocortex: A computational model. Cerebral Cortex, 24(2), 487–500. https://doi.org/10.1093/cercor/bhs327

Abstract

Abstract

Abstract

Injections of neural tracers into many mammalian neocortical areas reveal a common patchy motif of clustered axonal projections. We studied in simulation a mathematical model for neuronal development in order to investigate how this patchy connectivity could arise in layer II/III of the neocortex. In our model, individual neurons of this layer expressed the activator–inhibitor components of a Gierer–Meinhardt reaction–diffusion system. The resultant steady-state reaction–diffusion pattern across the neuronal population was approximate

Additional indexing

Creators (Authors)

  • Bauer, R
    affiliation.icon.alt
  • Zubler, F
    affiliation.icon.alt
  • Hauri, A
    affiliation.icon.alt
  • Muir, D R
    affiliation.icon.alt
  • Douglas, R J
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
24

Number

Number

Number
2

Page range/Item number

Page range/Item number

Page range/Item number
487

Page end

Page end

Page end
500

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2014

Date available

Date available

Date available
2013-03-07

Publisher

Publisher

Publisher

Series Name

Series Name

Series Name
Cerebral Cortex

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
1047-3211

OA Status

OA Status

OA Status
Hybrid

Free Access at

Free Access at

Free Access at
Pubmed ID

PubMed ID

PubMed ID

PubMed ID

Citations

Citation copied

Bauer, R., Zubler, F., Hauri, A., Muir, D. R., & Douglas, R. J. (2014). Developmental origin of patchy axonal connectivity in the neocortex: A computational model. Cerebral Cortex, 24(2), 487–500. https://doi.org/10.1093/cercor/bhs327

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