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Gray matter and white matter changes in non-demented amyotrophic lateral sclerosis patients with or without cognitive impairment: A combined voxel-based morphometry and tract-based spatial statistics whole-brain analysis

Date

Date

Date
2018
Journal Article
Published version

Citations

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Christidi, F., Karavasilis, E., Riederer, F., Zalonis, I., Ferentinos, P., Velonakis, G., Xirou, S., Rentzos, M., Argiropoulos, G., Zouvelou, V., Zambelis, T., Athanasakos, A., Toulas, P., Vadikolias, K., Efstathopoulos, E., Kollias, S., Karandreas, N., Kelekis, N., & Evdokimidis, I. (2018). Gray matter and white matter changes in non-demented amyotrophic lateral sclerosis patients with or without cognitive impairment: A combined voxel-based morphometry and tract-based spatial statistics whole-brain analysis. Brain Imaging and Behavior, 12(2), 547–563. https://doi.org/10.1007/s11682-017-9722-y

Abstract

Abstract

Abstract

The phenotypic heterogeneity in amyotrophic lateral sclerosis (ALS) implies that patients show structural changes within but also beyond the motor cortex and corticospinal tract and furthermore outside the frontal lobes, even if frank dementia is not detected. The aim of the present study was to investigate both gray matter (GM) and white matter (WM) changes in non-demented amyotrophic lateral sclerosis (ALS) patients with or without cognitive impairment (ALS-motor and ALS-plus, respectively). Nineteen ALS-motor, 31 ALS-plus and 25 he

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99 since deposited on 2018-02-01
98last week
Acq. date: 2025-11-13

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Creators (Authors)

  • Christidi, Foteini
    affiliation.icon.alt
  • Karavasilis, Efstratios
    affiliation.icon.alt
  • Riederer, Franz
    affiliation.icon.alt
  • Zalonis, Ioannis
    affiliation.icon.alt
  • Ferentinos, Panagiotis
    affiliation.icon.alt
  • Velonakis, Georgios
    affiliation.icon.alt
  • Xirou, Sophia
    affiliation.icon.alt
  • Rentzos, Michalis
    affiliation.icon.alt
  • Argiropoulos, Georgios
    affiliation.icon.alt
  • Zouvelou, Vasiliki
    affiliation.icon.alt
  • Zambelis, Thomas
    affiliation.icon.alt
  • Athanasakos, Athanasios
    affiliation.icon.alt
  • Toulas, Panagiotis
    affiliation.icon.alt
  • Vadikolias, Konstantinos
    affiliation.icon.alt
  • Efstathopoulos, Efstathios
    affiliation.icon.alt
  • Kollias, Spyros
    affiliation.icon.alt
  • Karandreas, Nikolaos
    affiliation.icon.alt
  • Kelekis, Nikolaos
    affiliation.icon.alt
  • Evdokimidis, Ioannis
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
12

Number

Number

Number
2

Page range/Item number

Page range/Item number

Page range/Item number
547

Page end

Page end

Page end
563

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2018

Date available

Date available

Date available
2018-02-01

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
1931-7557

OA Status

OA Status

OA Status
Closed

PubMed ID

PubMed ID

PubMed ID

Metrics

Views

99 since deposited on 2018-02-01
98last week
Acq. date: 2025-11-13

Citations

Citation copied

Christidi, F., Karavasilis, E., Riederer, F., Zalonis, I., Ferentinos, P., Velonakis, G., Xirou, S., Rentzos, M., Argiropoulos, G., Zouvelou, V., Zambelis, T., Athanasakos, A., Toulas, P., Vadikolias, K., Efstathopoulos, E., Kollias, S., Karandreas, N., Kelekis, N., & Evdokimidis, I. (2018). Gray matter and white matter changes in non-demented amyotrophic lateral sclerosis patients with or without cognitive impairment: A combined voxel-based morphometry and tract-based spatial statistics whole-brain analysis. Brain Imaging and Behavior, 12(2), 547–563. https://doi.org/10.1007/s11682-017-9722-y

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