Publication: Gray matter and white matter changes in non-demented amyotrophic lateral sclerosis patients with or without cognitive impairment: A combined voxel-based morphometry and tract-based spatial statistics whole-brain analysis
Gray matter and white matter changes in non-demented amyotrophic lateral sclerosis patients with or without cognitive impairment: A combined voxel-based morphometry and tract-based spatial statistics whole-brain analysis
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Christidi, F., Karavasilis, E., Riederer, F., Zalonis, I., Ferentinos, P., Velonakis, G., Xirou, S., Rentzos, M., Argiropoulos, G., Zouvelou, V., Zambelis, T., Athanasakos, A., Toulas, P., Vadikolias, K., Efstathopoulos, E., Kollias, S., Karandreas, N., Kelekis, N., & Evdokimidis, I. (2018). Gray matter and white matter changes in non-demented amyotrophic lateral sclerosis patients with or without cognitive impairment: A combined voxel-based morphometry and tract-based spatial statistics whole-brain analysis. Brain Imaging and Behavior, 12(2), 547–563. https://doi.org/10.1007/s11682-017-9722-y
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The phenotypic heterogeneity in amyotrophic lateral sclerosis (ALS) implies that patients show structural changes within but also beyond the motor cortex and corticospinal tract and furthermore outside the frontal lobes, even if frank dementia is not detected. The aim of the present study was to investigate both gray matter (GM) and white matter (WM) changes in non-demented amyotrophic lateral sclerosis (ALS) patients with or without cognitive impairment (ALS-motor and ALS-plus, respectively). Nineteen ALS-motor, 31 ALS-plus and 25 he
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Christidi, F., Karavasilis, E., Riederer, F., Zalonis, I., Ferentinos, P., Velonakis, G., Xirou, S., Rentzos, M., Argiropoulos, G., Zouvelou, V., Zambelis, T., Athanasakos, A., Toulas, P., Vadikolias, K., Efstathopoulos, E., Kollias, S., Karandreas, N., Kelekis, N., & Evdokimidis, I. (2018). Gray matter and white matter changes in non-demented amyotrophic lateral sclerosis patients with or without cognitive impairment: A combined voxel-based morphometry and tract-based spatial statistics whole-brain analysis. Brain Imaging and Behavior, 12(2), 547–563. https://doi.org/10.1007/s11682-017-9722-y