Publication: Hypothermia does not influence liver damage and function in a porcine polytrauma model
Hypothermia does not influence liver damage and function in a porcine polytrauma model
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Eschbach, D., Horst, K., Sassen, M., Andruszkow, J., Mohr, J., Debus, F., Vogt, N., Steinfeldt, T., Hildebrand, F., Schöller, K., Uhl, E., Wulf, H., Ruchholtz, S., Pape, H.-C., & Frink, M. (2018). Hypothermia does not influence liver damage and function in a porcine polytrauma model. Technology and Health Care, 26(2), 209–221. https://doi.org/10.3233/THC-171043
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BACKGROUND: Previous studies revealed evidence that induced hypothermia attenuates ischemic organ injuries after severe trauma. In the present study, the effect of hypothermia on liver damage was investigated in a porcine long term model of multi-system injury, consisting of blunt chest trauma, penetrating abdominal trauma, musculoskeletal injury, and hemorrhagic shock METHODS: In 30 pigs, a standardized polytrauma including blunt chest trauma, penetrating abdominal trauma, musculoskeletal injury, and hemorrhagic shock of 45% of total
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Eschbach, D., Horst, K., Sassen, M., Andruszkow, J., Mohr, J., Debus, F., Vogt, N., Steinfeldt, T., Hildebrand, F., Schöller, K., Uhl, E., Wulf, H., Ruchholtz, S., Pape, H.-C., & Frink, M. (2018). Hypothermia does not influence liver damage and function in a porcine polytrauma model. Technology and Health Care, 26(2), 209–221. https://doi.org/10.3233/THC-171043