Publication: The expression pattern of keratin 24 in tissue-engineered dermo-epidermal human skin substitutes in an in vivo model
The expression pattern of keratin 24 in tissue-engineered dermo-epidermal human skin substitutes in an in vivo model
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Klar, A. S., Michalak, K., Böttcher-Haberzeth, S., Reichmann, E., Meuli, M., & Biedermann, T. (2018). The expression pattern of keratin 24 in tissue-engineered dermo-epidermal human skin substitutes in an in vivo model. Pediatric Surgery International, 34(2), 237–244. https://doi.org/10.1007/s00383-017-4198-9
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AIMS AND OBJECTIVES: The use of autologous tissue-engineered skin substitutes is a promising approach to cover large skin defects in patients. Preclinical investigation is pivotal to test and improve the quality of these bio-engineered substitutes. In the skin, the epidermis, formed mainly by keratinocytes, provides the first physical barrier protecting from the environment. Proper keratinocyte differentiation and, thus, formation of a stratified epidermis is essential for this function. Keratins, the main structural support of kerati
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- Klar, Agnes S
- Michalak, Katarzyna
- Böttcher-Haberzeth, Sophie
- Reichmann, Ernst
- Meuli, Martin
- Biedermann, Thomas
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Klar, A. S., Michalak, K., Böttcher-Haberzeth, S., Reichmann, E., Meuli, M., & Biedermann, T. (2018). The expression pattern of keratin 24 in tissue-engineered dermo-epidermal human skin substitutes in an in vivo model. Pediatric Surgery International, 34(2), 237–244. https://doi.org/10.1007/s00383-017-4198-9