Publication:

Unexplored therapeutic opportunities in the human genome

Date

Date

Date
2018
Journal Article
Published version

Citations

Citation copied

Oprea, T. I., Bologa, C. G., Brunak, S., et al, & von Mering, C. (2018). Unexplored therapeutic opportunities in the human genome. Nature Reviews : Drug Discovery, 17(5), 317–332. https://doi.org/10.1038/nrd.2018.14

Abstract

Abstract

Abstract

A large proportion of biomedical research and the development of therapeutics is focused on a small fraction of the human genome. In a strategic effort to map the knowledge gaps around proteins encoded by the human genome and to promote the exploration of currently understudied, but potentially druggable, proteins, the US National Institutes of Health launched the Illuminating the Druggable Genome (IDG) initiative in 2014. In this article, we discuss how the systematic collection and processing of a wide array of genomic, proteomic, c

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226 since deposited on 2019-02-22
Acq. date: 2025-11-14

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118 since deposited on 2019-02-22
Acq. date: 2025-11-14

Additional indexing

Creators (Authors)

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
17

Number

Number

Number
5

Page range/Item number

Page range/Item number

Page range/Item number
317

Page end

Page end

Page end
332

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2018-05

Date available

Date available

Date available
2019-02-22

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
1474-1776

Additional Information

Additional Information

Additional Information
Erratum in Unexplored therapeutic opportunities in the human genome. [Nat Rev Drug Discov. 2018]

OA Status

OA Status

OA Status
Green

Free Access at

Free Access at

Free Access at
Pubmed ID

PubMed ID

PubMed ID

PubMed ID

Metrics

Downloads

226 since deposited on 2019-02-22
Acq. date: 2025-11-14

Views

118 since deposited on 2019-02-22
Acq. date: 2025-11-14

Citations

Citation copied

Oprea, T. I., Bologa, C. G., Brunak, S., et al, & von Mering, C. (2018). Unexplored therapeutic opportunities in the human genome. Nature Reviews : Drug Discovery, 17(5), 317–332. https://doi.org/10.1038/nrd.2018.14

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