Publication: Unexplored therapeutic opportunities in the human genome
Unexplored therapeutic opportunities in the human genome
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Oprea, T. I., Bologa, C. G., Brunak, S., et al, & von Mering, C. (2018). Unexplored therapeutic opportunities in the human genome. Nature Reviews : Drug Discovery, 17(5), 317–332. https://doi.org/10.1038/nrd.2018.14
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A large proportion of biomedical research and the development of therapeutics is focused on a small fraction of the human genome. In a strategic effort to map the knowledge gaps around proteins encoded by the human genome and to promote the exploration of currently understudied, but potentially druggable, proteins, the US National Institutes of Health launched the Illuminating the Druggable Genome (IDG) initiative in 2014. In this article, we discuss how the systematic collection and processing of a wide array of genomic, proteomic, c
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Oprea, T. I., Bologa, C. G., Brunak, S., et al, & von Mering, C. (2018). Unexplored therapeutic opportunities in the human genome. Nature Reviews : Drug Discovery, 17(5), 317–332. https://doi.org/10.1038/nrd.2018.14