Publication: A small region on the X chromosome of Drosophila regulates a key gene that controls sex determination and dosage compensation.
A small region on the X chromosome of Drosophila regulates a key gene that controls sex determination and dosage compensation.
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Steinmann-Zwicky, M., & Nöthiger, R. (1985). A small region on the X chromosome of Drosophila regulates a key gene that controls sex determination and dosage compensation. Cell, 42(3), 877–887. https://doi.org/10.1016/0092-8674(85)90284-3
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In Drosophila, flies with two X chromosomes are females, with one X chromosome, males. We investigated the presence of sex determining factors on the X chromosome by constructing genotypes with one X and various X-chromosomal duplications. We found that female determining factors are not evenly distributed along the X chromosome as had been previously postulated. A distal duplication covering 35% of the X chromosome promotes female differentiation, a much larger proximal duplication of 60% results in male differentiation. The strong f
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- Nöthiger, R
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Steinmann-Zwicky, M., & Nöthiger, R. (1985). A small region on the X chromosome of Drosophila regulates a key gene that controls sex determination and dosage compensation. Cell, 42(3), 877–887. https://doi.org/10.1016/0092-8674(85)90284-3
