Publication: A Non-Classical Ontogenetic Path Gives Rise to a GM-CSF Dependent Macrophage Population in the Developing Salivary Gland
A Non-Classical Ontogenetic Path Gives Rise to a GM-CSF Dependent Macrophage Population in the Developing Salivary Gland
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Westermann, F. (2024). A Non-Classical Ontogenetic Path Gives Rise to a GM-CSF Dependent Macrophage Population in the Developing Salivary Gland. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-258841
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The cytokine granulocyte-macrophage colony stimulating factor (GM-CSF) has obtained a lot of attention for its role in inflammatory conditions, while its role in developmental and steady state myelopoiesis, beyond alveolar macrophages in the lung, remains incompletely understood. In this thesis, we identified GM-CSF to be crucial for the development and maintenance of a macrophage subset in the salivary gland (SG). Macrophages make up the predominant part of the immune compartment in the SG, but their origin and functional repertoire
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Westermann, F. (2024). A Non-Classical Ontogenetic Path Gives Rise to a GM-CSF Dependent Macrophage Population in the Developing Salivary Gland. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-258841