Publication: The canalicular bile salt export pump BSEP (ABCB11) as a potential therapeutic target
The canalicular bile salt export pump BSEP (ABCB11) as a potential therapeutic target
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Stieger, B., & Beuers, U. (2011). The canalicular bile salt export pump BSEP (ABCB11) as a potential therapeutic target. Current Drug Targets, 12(5), 661–670. https://doi.org/10.2174/138945011795378496
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Bile formation is a key function of the liver and is driven by active secretion of bile salts and other organic compounds into the biliary tree. Bile salts represent the major organic constituent of bile. They are released with bile into the small intestine, where they are almost quantitatively reabsorbed and transported via the portal circulation back to the liver. In the liver, they are taken up into hepatocytes and secreted into bile. This cycling between the liver and the small intestine is called enterohepatic circulation of bile
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- Stieger, B
- Beuers, U
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Stieger, B., & Beuers, U. (2011). The canalicular bile salt export pump BSEP (ABCB11) as a potential therapeutic target. Current Drug Targets, 12(5), 661–670. https://doi.org/10.2174/138945011795378496
