Publication: Circulating Long Noncoding RNA Signatures Associate With Incident Diabetes in Older Adults: A Prospective Analysis From the VITA Cohort Study
Circulating Long Noncoding RNA Signatures Associate With Incident Diabetes in Older Adults: A Prospective Analysis From the VITA Cohort Study
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Wenzl, F. A., Mengozzi, A., Mohammed, S. A., Pugliese, N. R., Mongelli, A., Gorica, E., Ambrosini, S., Riederer, P., Fischer, P., Hinterberger, M., Puspitasari, Y., Lüscher, T. F., Camici, G. G., Matter, C. M., Fadini, G. P., Virdis, A., Masi, S., Ruschitzka, F., Grünblatt, E., … Costantino, S. (2023). Circulating Long Noncoding RNA Signatures Associate With Incident Diabetes in Older Adults: A Prospective Analysis From the VITA Cohort Study. Diabetes Care, 46, 1239–1244. https://doi.org/10.2337/dc23-0012
Abstract
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Objective: Long noncoding RNAs (lncRNAs) are involved in diabetogenesis in experimental models, yet their role in humans is unclear. We investigated whether circulating lncRNAs associate with incident type 2 diabetes in older adults.
Research design and methods: A preselected panel of lncRNAs was measured in serum of individuals without diabetes (n = 296) from the Vienna Transdanube Aging study, a prospective community-based cohort study. Participants were followed up over 7.5 years. A second cohort of individuals with and without ty
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- Wenzl, Florian A
- Mengozzi, Alessandro
- Mohammed, Shafeeq A
- Pugliese, Nicola Riccardo
- Mongelli, Alessia
- Gorica, Era
- Ambrosini, Samuele
- Riederer, Peter
- Fischer, Peter
- Hinterberger, Margareta
- Lüscher, Thomas F
- Camici, Giovanni G
- Matter, Christian M
- Fadini, Gian Paolo
- Virdis, Agostino
- Masi, Stefano
- Ruschitzka, Frank
- Paneni, Francesco
- Costantino, Sarah
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Wenzl, F. A., Mengozzi, A., Mohammed, S. A., Pugliese, N. R., Mongelli, A., Gorica, E., Ambrosini, S., Riederer, P., Fischer, P., Hinterberger, M., Puspitasari, Y., Lüscher, T. F., Camici, G. G., Matter, C. M., Fadini, G. P., Virdis, A., Masi, S., Ruschitzka, F., Grünblatt, E., … Costantino, S. (2023). Circulating Long Noncoding RNA Signatures Associate With Incident Diabetes in Older Adults: A Prospective Analysis From the VITA Cohort Study. Diabetes Care, 46, 1239–1244. https://doi.org/10.2337/dc23-0012
