Publication: Pharmacokinetics of the calcium-channel blocker diltiazem after a single intravenous dose in horses
Pharmacokinetics of the calcium-channel blocker diltiazem after a single intravenous dose in horses
Date
Date
Date
Citations
Schwarzwald, C. C., Sams, R. A., & Bonagura, J. D. (2006). Pharmacokinetics of the calcium-channel blocker diltiazem after a single intravenous dose in horses. Journal of Veterinary Pharmacology and Therapeutics, 29(3), 165–171. https://doi.org/10.1111/j.1365-2885.2006.00733.x
Abstract
Abstract
Abstract
The pharmacokinetics of diltiazem were determined in eight healthy horses. Diltiazem HCl, 1 mg/kg i.v., was administered over 5 min. Venous blood samples were collected at regular intervals after administration. Plasma concentrations of diltiazem and desacetyldiltiazem were determined by high-performance liquid chromatography. A second, putative metabolite was detected, but could not be identified due to the lack of an authentic standard. Data were analyzed by nonlinear least-squares regression analysis. The median (minimum-maximum) p
Additional indexing
Creators (Authors)
- Sams, R A
- Bonagura, J D
Journal/Series Title
Journal/Series Title
Journal/Series Title
Volume
Volume
Volume
Number
Number
Number
Page range/Item number
Page range/Item number
Page range/Item number
Page end
Page end
Page end
Item Type
Item Type
Item Type
In collections
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Free Access at
Free Access at
Free Access at
Publisher DOI
Citations
Schwarzwald, C. C., Sams, R. A., & Bonagura, J. D. (2006). Pharmacokinetics of the calcium-channel blocker diltiazem after a single intravenous dose in horses. Journal of Veterinary Pharmacology and Therapeutics, 29(3), 165–171. https://doi.org/10.1111/j.1365-2885.2006.00733.x
