A curated collection of tissue microarray images and clinical outcome data of prostate cancer patients

Zhong, Qing; Guo, Tiannan; Rechsteiner, Markus; Rüschoff, Jan H; Rupp, Niels; Fankhauser, Christian; Saba, Karim; Mortezavi, Ashkan; Poyet, Cédric; Hermanns, Thomas; Zhu, Yi; Moch, Holger; Aebersold, Ruedi; Wild, Peter J

doi:10.5167/uzh-136857

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Zhong, Q., Guo, T., Rechsteiner, M., Rüschoff, J. H., Rupp, N., Fankhauser, C., Saba, K., Mortezavi, A., Poyet, C., Hermanns, T., Zhu, Y., Moch, H., Aebersold, R., & Wild, P. J. (2017). A curated collection of tissue microarray images and clinical outcome data of prostate cancer patients. Scientific Data, 4, 170014. https://doi.org/10.1038/sdata.2017.14

Abstract

Microscopy image data of human cancers provide detailed phenotypes of spatially and morphologically intact tissues at single-cell resolution, thus complementing large-scale molecular analyses, e.g., next generation sequencing or proteomic profiling. Here we describe a high-resolution tissue microarray (TMA) image dataset from a cohort of 71 prostate tissue samples, which was hybridized with bright-field dual colour chromogenic and silver in situ hybridization probes for the tumour suppressor gene PTEN. These tissue samples were digiti