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Prostate-specific membrane antigen: A promising protein target for improved imaging and therapy of prostate cancer

Date

Date

Date
2023
Habilitation

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Kranzbühler, B. R. M. (2023). Prostate-specific membrane antigen: A promising protein target for improved imaging and therapy of prostate cancer. (Habilitation, University of Zurich) https://doi.org/10.5167/uzh-258575

Abstract

Abstract

Abstract

Prostate-specific membrane antigen (PSMA) is a type II transmembrane protein that is highly expressed in 85%-95% of all prostate cancer (PCa) lesions. Histological tissue analyses show a gradually increasing PSMA expression from benign prostate tissue to adenocarcinoma of the prostate. Therefore, PSMA turned into one of the most important PCa cell-surface markers, and is increasingly used for imaging and therapy of PCa. The first three articles discussed in this work evaluate the performance of $^{68}$Ga-PSMA-11 PET/MRI and $^{68}$

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6 since deposited on 2024-03-18
Acq. date: 2025-11-12

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57 since deposited on 2024-03-18
Acq. date: 2025-11-12

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Creators (Authors)

  • Kranzbühler, Benedikt Roman Maria

Institution

Institution

Institution

Faculty

Faculty

Faculty
Faculty of Medicine

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Item Type

Item Type
Habilitation

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Dewey Decimal Classifikation

Dewey Decimal Classifikation

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Language
English

Publication date

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Publication date
2023-01-04

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Date available
2024-03-18

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OA Status
Closed

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6 since deposited on 2024-03-18
Acq. date: 2025-11-12

Views

57 since deposited on 2024-03-18
Acq. date: 2025-11-12

Citations

Citations

Citation copied

Kranzbühler, B. R. M. (2023). Prostate-specific membrane antigen: A promising protein target for improved imaging and therapy of prostate cancer. (Habilitation, University of Zurich) https://doi.org/10.5167/uzh-258575

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