Publication:

The Roles of $\textit{MSH6}$ in Tumor Progression and Radiotherapy Response in Glioblastoma

Date

Date

Date
2024
Dissertation

Citations

Citation copied

Lourman, R. (2024). The Roles of $\textit{MSH6}$ in Tumor Progression and Radiotherapy Response in Glioblastoma. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-267132

Abstract

Abstract

Abstract

Glioblastoma is the most common and most aggressive primary brain tumor in adults and is currently incurable. Glioblastomas revert a poor prognosis despite multimodal first line treatment comprising surgical tumor resection followed by radiochemotherapy with the DNA-methylating agent, temozolomide. Ultimately, the vast majority of glioblastomas progress within the first year following diagnosis due to resistance against temozolomide, limiting therapeutic options and mounting into nearly universal mortality of patients. Among othe

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94 since deposited on 2024-12-27
92last week
Acq. date: 2025-11-12

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Creators (Authors)

  • Lourman, Roxanne

Institution

Institution

Institution

Faculty

Faculty

Faculty
Faculty of Science

Item Type

Item Type

Item Type
Dissertation

Referees

  • Weller, Michael
  • Wirsching, Hans-Georg
  • Jessberger, Sebastian
  • Reifenberger, Guido

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Place of Publication

Place of Publication

Place of Publication
Zürich

Publication date

Publication date

Publication date
2024-12-27

Date available

Date available

Date available
2024-12-27

Number of pages

Number of pages

Number of pages
114

OA Status

OA Status

OA Status
Green

Metrics

Views

94 since deposited on 2024-12-27
92last week
Acq. date: 2025-11-12

Citations

Citations

Citation copied

Lourman, R. (2024). The Roles of $\textit{MSH6}$ in Tumor Progression and Radiotherapy Response in Glioblastoma. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-267132

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