Publication: The Roles of $\textit{MSH6}$ in Tumor Progression and Radiotherapy Response in Glioblastoma
The Roles of $\textit{MSH6}$ in Tumor Progression and Radiotherapy Response in Glioblastoma
Date
Date
Date
Citations
Lourman, R. (2024). The Roles of $\textit{MSH6}$ in Tumor Progression and Radiotherapy Response in Glioblastoma. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-267132
Abstract
Abstract
Abstract
Glioblastoma is the most common and most aggressive primary brain tumor in adults and is currently incurable. Glioblastomas revert a poor prognosis despite multimodal first line treatment comprising surgical tumor resection followed by radiochemotherapy with the DNA-methylating agent, temozolomide. Ultimately, the vast majority of glioblastomas progress within the first year following diagnosis due to resistance against temozolomide, limiting therapeutic options and mounting into nearly universal mortality of patients. Among othe
Additional indexing
Creators (Authors)
Faculty
Faculty
Faculty
Item Type
Item Type
Item Type
Referees
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
Place of Publication
Place of Publication
Place of Publication
Publication date
Publication date
Publication date
Date available
Date available
Date available
Number of pages
Number of pages
Number of pages
OA Status
OA Status
OA Status
Citations
Lourman, R. (2024). The Roles of $\textit{MSH6}$ in Tumor Progression and Radiotherapy Response in Glioblastoma. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-267132