Publication: OxyHbMeter—a novel bedside medical device for monitoring cell-free hemoglobin in the cerebrospinal fluid—proof of principle
OxyHbMeter—a novel bedside medical device for monitoring cell-free hemoglobin in the cerebrospinal fluid—proof of principle
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Tachatos, N., Willms, J. F., Gerlt, M. S., Kuruvithadam, K., Hugelshofer, M., Akeret, K., Deuel, J., Keller, E., & Schmid Daners, M. (2024). OxyHbMeter—a novel bedside medical device for monitoring cell-free hemoglobin in the cerebrospinal fluid—proof of principle. Frontiers in Medical Technology, 6, 1274058. https://doi.org/10.3389/fmedt.2024.1274058
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Delayed cerebral ischemia (DCI) occurs in up to one third of patients suffering from aneurysmal subarachnoid hemorrhage (aSAH). Untreated, it leads to secondary cerebral infarctions and is frequently associated with death or severe disability. After aneurysm rupture, erythrocytes in the subarachnoid space lyse and liberate free hemoglobin (Hb), a key driver for the development of DCI. Hemoglobin in the cerebrospinal fluid (CSF-Hb) can be analyzed through a two-step procedure of centrifugation to exclude intact erythrocytes and subsequ
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Tachatos, N., Willms, J. F., Gerlt, M. S., Kuruvithadam, K., Hugelshofer, M., Akeret, K., Deuel, J., Keller, E., & Schmid Daners, M. (2024). OxyHbMeter—a novel bedside medical device for monitoring cell-free hemoglobin in the cerebrospinal fluid—proof of principle. Frontiers in Medical Technology, 6, 1274058. https://doi.org/10.3389/fmedt.2024.1274058