Publication:

OxyHbMeter—a novel bedside medical device for monitoring cell-free hemoglobin in the cerebrospinal fluid—proof of principle

Date

Date

Date
2024
Journal Article
Published version

Citations

Citation copied

Tachatos, N., Willms, J. F., Gerlt, M. S., Kuruvithadam, K., Hugelshofer, M., Akeret, K., Deuel, J., Keller, E., & Schmid Daners, M. (2024). OxyHbMeter—a novel bedside medical device for monitoring cell-free hemoglobin in the cerebrospinal fluid—proof of principle. Frontiers in Medical Technology, 6, 1274058. https://doi.org/10.3389/fmedt.2024.1274058

Abstract

Abstract

Abstract

Delayed cerebral ischemia (DCI) occurs in up to one third of patients suffering from aneurysmal subarachnoid hemorrhage (aSAH). Untreated, it leads to secondary cerebral infarctions and is frequently associated with death or severe disability. After aneurysm rupture, erythrocytes in the subarachnoid space lyse and liberate free hemoglobin (Hb), a key driver for the development of DCI. Hemoglobin in the cerebrospinal fluid (CSF-Hb) can be analyzed through a two-step procedure of centrifugation to exclude intact erythrocytes and subsequ

Additional indexing

Creators (Authors)

  • Tachatos, Nikolaos
    affiliation.icon.alt
  • Willms, Jan Folkard
    affiliation.icon.alt
  • Gerlt, Michael Sebastian
    affiliation.icon.alt
  • Kuruvithadam, Kiran
    affiliation.icon.alt
  • Hugelshofer, Michael
    affiliation.icon.alt
  • Akeret, Kevin
    affiliation.icon.alt
  • Deuel, Jeremy
    affiliation.icon.alt
  • Schmid Daners, Marianne
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
6

Page range/Item number

Page range/Item number

Page range/Item number
1274058

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Keywords

acoustic particle manipulation, aneurysmal subarachnoid hemorrhage, cell separation, centrifugation, delayed cerebral ischemia, microfluidics, point of care device, pectrophotometry

Language

Language

Language
English

Publication date

Publication date

Publication date
2024-04-11

Date available

Date available

Date available
2024-05-02

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
2673-3129

OA Status

OA Status

OA Status
Gold

Free Access at

Free Access at

Free Access at
DOI

PubMed ID

PubMed ID

PubMed ID

Citations

Citation copied

Tachatos, N., Willms, J. F., Gerlt, M. S., Kuruvithadam, K., Hugelshofer, M., Akeret, K., Deuel, J., Keller, E., & Schmid Daners, M. (2024). OxyHbMeter—a novel bedside medical device for monitoring cell-free hemoglobin in the cerebrospinal fluid—proof of principle. Frontiers in Medical Technology, 6, 1274058. https://doi.org/10.3389/fmedt.2024.1274058

Gold Open Access
Loading...
Thumbnail Image

Files

Files

Files
Files available to download:3
Show more files

Files

Files

Files
Files available to download:3
Loading...
Thumbnail Image
Show more files