Publication: Toward community standards in the quest for orthologs
Toward community standards in the quest for orthologs
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Dessimoz, C., Gabaldon, T., Roos, D. S., Sonnhammer, E. L. L., Herrero, J., Altenhoff, A., Apweiler, R., Ashburner, M., Blake, J., Boeckmann, B., Bridge, A., Bruford, E., Cherry, M., Conte, M., Dannie, D., Datta, R., Dessimoz, C., Domelevo Entfellner, J.-B., Ebersberger, I., … et al. (2012). Toward community standards in the quest for orthologs. Bioinformatics, 28(6), 900–904. https://doi.org/10.1093/bioinformatics/bts050
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The identification of orthologs—genes pairs descended from a common ancestor through speciation, rather than duplication—has emerged as an essential component of many bioinformatics applications, ranging from the annotation of new genomes to experimental target prioritization. Yet, the development and application of orthology inference methods is hampered by the lack of consensus on source proteomes, file formats and benchmarks. The second ‘Quest for Orthologs' meeting brought together stakeholders from various communities to address
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- Dessimoz, C
- Gabaldon, T
- Roos, D S
- Sonnhammer, E L L
- Herrero, J
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Dessimoz, C., Gabaldon, T., Roos, D. S., Sonnhammer, E. L. L., Herrero, J., Altenhoff, A., Apweiler, R., Ashburner, M., Blake, J., Boeckmann, B., Bridge, A., Bruford, E., Cherry, M., Conte, M., Dannie, D., Datta, R., Dessimoz, C., Domelevo Entfellner, J.-B., Ebersberger, I., … et al. (2012). Toward community standards in the quest for orthologs. Bioinformatics, 28(6), 900–904. https://doi.org/10.1093/bioinformatics/bts050
