Publication: Enhanced differentiation of human osteoblasts on Ti surfaces pre-treated with human whole blood
Enhanced differentiation of human osteoblasts on Ti surfaces pre-treated with human whole blood
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Kopf, B. S., Schipanski, A., Rottmar, M., Berner, S., & Maniura-Weber, K. (2015). Enhanced differentiation of human osteoblasts on Ti surfaces pre-treated with human whole blood. Acta Biomaterialia, 19, 180–190. https://doi.org/10.1016/j.actbio.2015.03.022
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Early and effective integration of a metal implant into bone tissue is of crucial importance for its long-term stability. While different material properties including surface roughness and wettability but also initial blood-implant surface interaction are known to influence this osseointegration, implications of the latter process are still poorly understood. In this study, early interaction between blood and the implant surface and how this affects the mechanism of osseointegration were investigated. For this, blood coagulation on a
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Kopf, B. S., Schipanski, A., Rottmar, M., Berner, S., & Maniura-Weber, K. (2015). Enhanced differentiation of human osteoblasts on Ti surfaces pre-treated with human whole blood. Acta Biomaterialia, 19, 180–190. https://doi.org/10.1016/j.actbio.2015.03.022