Publication: Altered regional connectivity reflecting effects of different anaesthesia protocols in the mouse brain
Altered regional connectivity reflecting effects of different anaesthesia protocols in the mouse brain
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Wu, T., Grandjean, J., Bosshard, S. C., Rudin, M., Reutens, D., & Jiang, T. (2017). Altered regional connectivity reflecting effects of different anaesthesia protocols in the mouse brain. NeuroImage, 149, 190–199. https://doi.org/10.1016/j.neuroimage.2017.01.074
Abstract
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Abstract
Studies in mice using resting-state functional magnetic resonance imaging (rs-fMRI) have provided opportunities to investigate the effects of pharmacological manipulations on brain function and map the phenotypes of mouse models of human brain disorders. Mouse rs-fMRI is typically performed under anaesthesia, which induces both regional suppression of brain activity and disruption of large-scale neural networks. Previous comparative studies using rodents investigating various drug effects on long-distance functional connectivity (FC)
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- Wu, Tong
- Grandjean, Joanes
- Bosshard, Simone C
- Rudin, Markus
- Reutens, David
- Jiang, Tianzi
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Citations
Wu, T., Grandjean, J., Bosshard, S. C., Rudin, M., Reutens, D., & Jiang, T. (2017). Altered regional connectivity reflecting effects of different anaesthesia protocols in the mouse brain. NeuroImage, 149, 190–199. https://doi.org/10.1016/j.neuroimage.2017.01.074
