Publication: Subversion of retrograde trafficking by translocated pathogen effectors
Subversion of retrograde trafficking by translocated pathogen effectors
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Personnic, N., Bärlocher, K., Finsel, I., & Hilbi, H. (2016). Subversion of retrograde trafficking by translocated pathogen effectors. Trends in Microbiology, 24(6), 450–462. https://doi.org/10.1016/j.tim.2016.02.003
Abstract
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Intracellular bacterial pathogens subvert the endocytic bactericidal pathway to form specific replication-permissive compartments termed pathogen vacuoles or inclusions. To this end, the pathogens employ type III or type IV secretion systems, which translocate dozens, if not hundreds, of different effector proteins into their host cells, where they manipulate vesicle trafficking and signaling pathways in favor of the intruders. While the distinct cocktail of effectors defines the specific processes by which a pathogen vacuole is forme
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- Personnic, Nicolas
- Bärlocher, Kevin
- Finsel, Ivo
- Hilbi, Hubert
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Personnic, N., Bärlocher, K., Finsel, I., & Hilbi, H. (2016). Subversion of retrograde trafficking by translocated pathogen effectors. Trends in Microbiology, 24(6), 450–462. https://doi.org/10.1016/j.tim.2016.02.003
