Publication: Changes in mRNA expression levels of solute carrier transporters in inflammatory bowel disease patients
Changes in mRNA expression levels of solute carrier transporters in inflammatory bowel disease patients
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Wojtal, K. A., Eloranta, J. J., Hruz, P., Gutmann, H., Drewe, J., Beglinger, C., Fried, M., Kullak-Ublick, G. A., & Vavricka, S. R. (2009). Changes in mRNA expression levels of solute carrier transporters in inflammatory bowel disease patients. Drug Metabolism and Disposition, 37(9), 1871–1877. https://doi.org/10.1124/dmd.109.027367
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Inflammatory bowel disease (IBD) is an inflammatory condition that affects gastrointestinal tract. Solute carrier superfamilly of transporters (SLC) comprise proteins involved in the uptake of drugs, hormones, and other biologically active compounds. The purpose of this study was to determine the mRNA expression levels of 15 solute carrier transporters in two regions of the intestine in IBD patients. Endoscopic biopsies were taken from two locations (terminal ileum and colon) for histological examination and RNA extraction. We quantit
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- Wojtal, K A
- Eloranta, J J
- Hruz, P
- Gutmann, H
- Drewe, J
- Beglinger, C
- Fried, M
- Kullak-Ublick, G A
- Vavricka, S R
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Wojtal, K. A., Eloranta, J. J., Hruz, P., Gutmann, H., Drewe, J., Beglinger, C., Fried, M., Kullak-Ublick, G. A., & Vavricka, S. R. (2009). Changes in mRNA expression levels of solute carrier transporters in inflammatory bowel disease patients. Drug Metabolism and Disposition, 37(9), 1871–1877. https://doi.org/10.1124/dmd.109.027367
