Publication: Gastrointestinal, Behaviour and Anxiety Outcomes in Autistic Children Following an Open Label, Randomised Pilot Study of Synbiotics vs Synbiotics and Gut-Directed Hypnotherapy
Gastrointestinal, Behaviour and Anxiety Outcomes in Autistic Children Following an Open Label, Randomised Pilot Study of Synbiotics vs Synbiotics and Gut-Directed Hypnotherapy
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Mitchell, L. K., Heussler, H. S., Burgess, C. J., Rehman, A., Steinert, R. E., & Davies, P. S. W. (2026). Gastrointestinal, Behaviour and Anxiety Outcomes in Autistic Children Following an Open Label, Randomised Pilot Study of Synbiotics vs Synbiotics and Gut-Directed Hypnotherapy. Journal of Autism and Developmental Disorders, 56, 1027–1045. https://doi.org/10.1007/s10803-024-06588-9
Abstract
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Abstract
Alterations of the microbiome-gut-brain (MGB) axis have been associated with autism spectrum disorder (ASD) and disorders of gut-brain interaction (DGBI). DGBI are highly prevalent in autistic children and are associated with worsening behaviour and anxiety. Treatments such as probiotics, prebiotics and gut-directed hypnotherapy (GDH) have shown efficacy in improving gut symptoms in children. The primary objective of the study was to compare changes in gastrointestinal (GI) scores following a 12-week intervention of synbiotics (prebio
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Creators (Authors)
- Mitchell, Leanne K
- Heussler, Helen S
- Burgess, Christopher J
- Rehman, Ateequr
- Steinert, Robert E
- Davies, Peter S W
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Mitchell, L. K., Heussler, H. S., Burgess, C. J., Rehman, A., Steinert, R. E., & Davies, P. S. W. (2026). Gastrointestinal, Behaviour and Anxiety Outcomes in Autistic Children Following an Open Label, Randomised Pilot Study of Synbiotics vs Synbiotics and Gut-Directed Hypnotherapy. Journal of Autism and Developmental Disorders, 56, 1027–1045. https://doi.org/10.1007/s10803-024-06588-9
