Publication: Intercompartmental communication between the cerebrospinal and adjacent spaces during intrathecal infusions in an acute ovine in-vivo model
Intercompartmental communication between the cerebrospinal and adjacent spaces during intrathecal infusions in an acute ovine in-vivo model
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Podgoršak, A., Trimmel, N. E., Oertel, M. F., Qvarlander, S., Arras, M., Eklund, A., Weisskopf, M., & Schmid Daners, M. (2022). Intercompartmental communication between the cerebrospinal and adjacent spaces during intrathecal infusions in an acute ovine in-vivo model. Fluids and Barriers of the CNS, 19, 2. https://doi.org/10.1186/s12987-021-00300-0
Abstract
Abstract
Abstract
INTRODUCTION
The treatment of hydrocephalus has been a topic of intense research ever since the first clinically successful use of a valved cerebrospinal fluid shunt 72 years ago. While ample studies elucidating different phenomena impacting this treatment exist, there are still gaps to be filled. Specifically, how intracranial, intrathecal, arterial, and venous pressures react and communicate with each other simultaneously.
METHODS
An in-vivo sheep trial (n = 6) was conducted to evaluate and quantify the communication existing wit
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Creators (Authors)
- Podgoršak, Anthony
- Trimmel, Nina Eva
- Oertel, Markus Florian
- Qvarlander, Sara
- Arras, Margarete
- Eklund, Anders
- Weisskopf, Miriam
- Schmid Daners, Marianne
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Podgoršak, A., Trimmel, N. E., Oertel, M. F., Qvarlander, S., Arras, M., Eklund, A., Weisskopf, M., & Schmid Daners, M. (2022). Intercompartmental communication between the cerebrospinal and adjacent spaces during intrathecal infusions in an acute ovine in-vivo model. Fluids and Barriers of the CNS, 19, 2. https://doi.org/10.1186/s12987-021-00300-0
