J-wave duration and slope as potential tools to discriminate between benign and malignant early repolarization

Cristoforetti, Yvonne; Biasco, Luigi; Giustetto, Carla; De Backer, Ole; Castagno, Davide; Astegiano, Piero; Ganzit, Gianpasquale; Gribaudo, Carlo Gabriele; Moccetti, Marco; Gaita, Fiorenzo

doi:10.1016/j.hrthm.2015.11.029

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Cristoforetti, Y., Biasco, L., Giustetto, C., De Backer, O., Castagno, D., Astegiano, P., Ganzit, G., Gribaudo, C. G., Moccetti, M., & Gaita, F. (2016). J-wave duration and slope as potential tools to discriminate between benign and malignant early repolarization. Heart Rhythm, 13(3), 806–811. https://doi.org/10.1016/j.hrthm.2015.11.029

Abstract

Interest in early repolarization (ER) increased after the theoretical proposal1 and the clinical demonstration2 that certain electrocardiographic (ECG) patterns characterized by an elevation of the J point were associated with an increased risk of sudden cardiac death in otherwise healthy individuals. Previous studies showed that only the rare pattern characterized by a significant J-point elevation (≥2 mm) in the inferior leads associated with a slurred J wave and a horizontal/descending ST segment was associated with an increased ri