Publication: Splitting of circulating red blood cells as -mechanism of erythrocyte maturation in developing zebrafish, chick and mouse embryos
Splitting of circulating red blood cells as -mechanism of erythrocyte maturation in developing zebrafish, chick and mouse embryos
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Brönnimann, D., Annese, T., Gorr, T. A., & Djonov, V. (2018). Splitting of circulating red blood cells as -mechanism of erythrocyte maturation in developing zebrafish, chick and mouse embryos. Journal of Experimental Biology, 221(Pt 15), jeb184564. https://doi.org/10.1242/jeb.184564
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Nucleated circulating red blood cells (RBCs) of developing zebrafish, chick and mouse embryos can actively proliferate. While marrow- or organ-mediated erythropoiesis has been widely studied, transforming processes of circulating RBCs are under little scrutiny. We employed confocal, stereo- and electron microscopy to document the maturation of intravascular RBCs. In zebrafish embryos (32-72 hours post fertilization), in the caudal vein plexus follows a four-step program: (i) Nuclear division with continued cytoplasmic connection bet
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Brönnimann, D., Annese, T., Gorr, T. A., & Djonov, V. (2018). Splitting of circulating red blood cells as -mechanism of erythrocyte maturation in developing zebrafish, chick and mouse embryos. Journal of Experimental Biology, 221(Pt 15), jeb184564. https://doi.org/10.1242/jeb.184564