Publication: Adequacy and sufficiency evaluation of existing EFSA guidelines for the molecular characterisation, environmental risk assessment and post‐market environmental monitoring of genetically modified insects containing engineered gene drives
Adequacy and sufficiency evaluation of existing EFSA guidelines for the molecular characterisation, environmental risk assessment and post‐market environmental monitoring of genetically modified insects containing engineered gene drives
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Naegeli, H., Bresson, J., Dalmay, T., Dewhurst, I. C., Epstein, M. M., Guerche, P., Hejatko, J., Moreno, F. J., Mullins, E., Nogué, F., Rostoks, N., Sánchez Serrano, J. J., Savoini, G., Veromann, E., Veronesi, F., Bonsall, M. B., Mumford, J., Wimmer, E. A., Devos, Y., … Firbank, L. G. (2020). Adequacy and sufficiency evaluation of existing EFSA guidelines for the molecular characterisation, environmental risk assessment and post‐market environmental monitoring of genetically modified insects containing engineered gene drives. EFSA Journal, 18(11), e06297. https://doi.org/10.2903/j.efsa.2020.6297
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Advances in molecular and synthetic biology are enabling the engineering of gene drives in insects for disease vector/pest control. Engineered gene drives (that bias their own inheritance) can be designed either to suppress interbreeding target populations or modify them with a new genotype. Depending on the engineered gene drive system, theoretically, a genetic modification of interest could spread through target populations and persist indefinitely, or be restricted in its spread or persistence. While research on engineered gene dri
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Naegeli, H., Bresson, J., Dalmay, T., Dewhurst, I. C., Epstein, M. M., Guerche, P., Hejatko, J., Moreno, F. J., Mullins, E., Nogué, F., Rostoks, N., Sánchez Serrano, J. J., Savoini, G., Veromann, E., Veronesi, F., Bonsall, M. B., Mumford, J., Wimmer, E. A., Devos, Y., … Firbank, L. G. (2020). Adequacy and sufficiency evaluation of existing EFSA guidelines for the molecular characterisation, environmental risk assessment and post‐market environmental monitoring of genetically modified insects containing engineered gene drives. EFSA Journal, 18(11), e06297. https://doi.org/10.2903/j.efsa.2020.6297
