Publication: Acid bone lysates reduce bone regeneration in rat calvaria defects
Acid bone lysates reduce bone regeneration in rat calvaria defects
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Strauss, F.-J., Kuchler, U., Kobatake, R., Heimel, P., Tangl, S., & Gruber, R. (2021). Acid bone lysates reduce bone regeneration in rat calvaria defects. Journal of Biomedical Materials Research. Part A, 109(5), 659–665. https://doi.org/10.1002/jbm.a.37050
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Acid bone lysates (ABLs) represent the growth factors and other molecules released during autologous graft resorption. However, the impact of these bone-derived growth factors on the healing of bone defects has not yet been investigated. The aim of the present study was, therefore, to examine the impact of ABLs adsorbed to collagen membranes on bone regeneration. To this end, in 16 female Sprague Dawley rats, a standardized 5-mm-diameter critical size defect on the calvarial bone was created. The defects were covered with collagen mem
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Strauss, F.-J., Kuchler, U., Kobatake, R., Heimel, P., Tangl, S., & Gruber, R. (2021). Acid bone lysates reduce bone regeneration in rat calvaria defects. Journal of Biomedical Materials Research. Part A, 109(5), 659–665. https://doi.org/10.1002/jbm.a.37050