Publication: Preventing vasospasm improves outcome after aneurysmal subarachnoid hemorrhage: rationale and design of CONSCIOUS-2 and CONSCIOUS-3 trials
Date
Date
Date
2010
Journal Article
Published version
Abstract
Abstract
Abstract
Cerebral vasospasm after aneurysmal subarachnoid hemorrhage (aSAH) is a frequent but unpredictable complication associated with poor outcome. Current vasospasm therapies are suboptimal; new therapies are needed. Clazosentan, an endothelin receptor antagonist, has shown promise in phase 2 studies, and two randomized, double-blind, placebo-controlled phase 3 trials (CONSCIOUS-2 and CONSCIOUS-3) are underway to further investigate its impact on vasospasm-related outcome after aSAH. Here we describe the design of these studies, which was
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376 since deposited on 2011-02-09
Acq. date: 2025-11-13
Views
346 since deposited on 2011-02-09
Acq. date: 2025-11-13
Additional indexing
Creators (Authors)
- Keller, E
- Mayer, S A
- Molyneux, A
- Raabe, A
- Vajkoczy, P
- Wanke, I
- Frey, A
- Marr, A
- Roux, S
Volume
Volume
Volume
13
Number
Number
Number
3
Page range/Item number
Page range/Item number
Page range/Item number
416
Page end
Page end
Page end
424
Item Type
Item Type
Item Type
Journal Article
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
English
Publication date
Publication date
Publication date
2010
Date available
Date available
Date available
2011-02-09
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
1541-6933
Additional Information
Additional Information
Additional Information
The original publication is available at www.springerlink.com
OA Status
OA Status
OA Status
Green
Publisher DOI
Metrics
Downloads
376 since deposited on 2011-02-09
Acq. date: 2025-11-13
Views
346 since deposited on 2011-02-09
Acq. date: 2025-11-13
Green Open Access
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