Publication: Circulating blood cells and extracellular vesicles in acute cardioprotection
Circulating blood cells and extracellular vesicles in acute cardioprotection
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Davidson, S. M., Andreadou, I., Barile, L., Birnbaum, Y., Cabrera-Fuentes, H. A., Cohen, M. V., Downey, J. M., Girao, H., Pagliaro, P., Penna, C., Pernow, J., Preissner, K. T., & Ferdinandy, P. (2019). Circulating blood cells and extracellular vesicles in acute cardioprotection. Cardiovascular Research, 115(7), 1156–1166. https://doi.org/10.1093/cvr/cvy314
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During an ST-elevation myocardial infarction (STEMI), the myocardium undergoes a prolonged period of ischaemia. Reperfusion therapy is essential to minimize cardiac injury but can paradoxically cause further damage. Experimental procedures to limit ischaemia and reperfusion (IR) injury have tended to focus on the cardiomyocytes since they are crucial for cardiac function. However, there is increasing evidence that non-cardiomyocyte resident cells in the heart (as discussed in a separate review in this Spotlight series) as well as circ
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Davidson, S. M., Andreadou, I., Barile, L., Birnbaum, Y., Cabrera-Fuentes, H. A., Cohen, M. V., Downey, J. M., Girao, H., Pagliaro, P., Penna, C., Pernow, J., Preissner, K. T., & Ferdinandy, P. (2019). Circulating blood cells and extracellular vesicles in acute cardioprotection. Cardiovascular Research, 115(7), 1156–1166. https://doi.org/10.1093/cvr/cvy314