Economic aspects of intraoperative coagulation management targeting higher fibrinogen concentrations during major craniosynostosis surgery

Haas, Thorsten; Spielmann, Nelly; Restin, Tanja; Schmidt, Alexander R; Schmugge, Markus; Cushing, Melissa M

doi:10.1111/pan.12784

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Haas, T., Spielmann, N., Restin, T., Schmidt, A. R., Schmugge, M., & Cushing, M. M. (2016). Economic aspects of intraoperative coagulation management targeting higher fibrinogen concentrations during major craniosynostosis surgery. Paediatric Anaesthesia, 26(1), 77–83. https://doi.org/10.1111/pan.12784

Abstract

BACKGROUND Results of a previously published study demonstrated a significant decrease in transfusion requirements and calculated blood loss for pediatric major craniosynostosis surgery, if a ROTEM(®) FIBTEM trigger of <13 mm (early substitution group) was applied as compared to a trigger of <8 mm (conventional group). The aim of this study was a posthoc analysis of the costs for this coagulation management. METHODS The total volume as well as the number of units or bags for all transfused blood products and coagulation factors wer