Publication: Approaches to Establish Extracardiac Total Cavopulmonary Connections in Animal Models-A Review
Approaches to Establish Extracardiac Total Cavopulmonary Connections in Animal Models-A Review
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Granegger, M., Valencia, A., Quandt, D., Dave, H., Kretschmar, O., Hübler, M., & Schweiger, M. (2019). Approaches to Establish Extracardiac Total Cavopulmonary Connections in Animal Models-A Review. World Journal for Pediatric and Congenital Heart Surgery, 10, 81–89. https://doi.org/10.1177/2150135118802788
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BACKGROUND Long-term survival of patients with a single ventricle palliated with a Fontan procedure is still limited. No curative treatment options are available. To investigate the pathophysiology and potential treatment options, such as mechanical circulatory support (MCS), appropriate large animal models are required. The aim of this review was to analyze all full-text manuscripts presenting approaches for an extracardiac total cavopulmonary connection (TCPC) animal model to identify the feasibility and limitations in the acute and
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Granegger, M., Valencia, A., Quandt, D., Dave, H., Kretschmar, O., Hübler, M., & Schweiger, M. (2019). Approaches to Establish Extracardiac Total Cavopulmonary Connections in Animal Models-A Review. World Journal for Pediatric and Congenital Heart Surgery, 10, 81–89. https://doi.org/10.1177/2150135118802788