Publication: Current technical approaches to brain energy metabolism
Current technical approaches to brain energy metabolism
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Barros, L. F., Bolaños, J. P., Bonvento, G., Bouzier-Sore, A.-K., Brown, A., Hirrlinger, J., Kasparov, S., Kirchhoff, F., Murphy, A. N., Pellerin, L., Robinson, M. B., & Weber, B. (2018). Current technical approaches to brain energy metabolism. Glia, 66(6), 1138–1159. https://doi.org/10.1002/glia.23248
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Neuroscience is a technology-driven discipline and brain energy metabolism is no exception. Once satisfied with mapping metabolic pathways at organ level, we are now looking to learn what it is exactly that metabolic enzymes and transporters do and when, where do they reside, how are they regulated, and how do they relate to the specific functions of neurons, glial cells, and their subcellular domains and organelles, in different areas of the brain. Moreover, we aim to quantify the fluxes of metabolites within and between cells. Energ
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H2020
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666918
310030E-164271
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BATCure - Developing new therapies for Batten disease
An in vivo exploration of the metabolic coupling between glial cells and neurons upon cerebral activation and its importance for synaptic plasticity using cutting edge NMR spectroscopy approaches
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Barros, L. F., Bolaños, J. P., Bonvento, G., Bouzier-Sore, A.-K., Brown, A., Hirrlinger, J., Kasparov, S., Kirchhoff, F., Murphy, A. N., Pellerin, L., Robinson, M. B., & Weber, B. (2018). Current technical approaches to brain energy metabolism. Glia, 66(6), 1138–1159. https://doi.org/10.1002/glia.23248