Publication:

Microparticles stimulate angiogenesis by inducing ELR(+) CXC-chemokines in synovial fibroblasts

Date

Date

Date
2011
Journal Article
Published version

Citations

Citation copied

Reich, N., Beyer, C., Gelse, K., Akhmetshina, A., Dees, C., Zwerina, J., Schett, G., Distler, O., & Distler, J. H. W. (2011). Microparticles stimulate angiogenesis by inducing ELR(+) CXC-chemokines in synovial fibroblasts. Journal of Cellular and Molecular Medicine, 15(4), 756–762. https://doi.org/10.1111/j.1582-4934.2010.01051.x

Abstract

Abstract

Abstract

Microparticles (MPs) are small membrane-vesicles that accumulate in the synovial fluids of patients with rheumatoid arthritis (RA). In the arthritic joints, MPs induce a pro-inflammatory and invasive phenotype in synovial fibroblasts (SFs). The present study investigated whether activation of SFs by MPs stimulates angiogenesis in the inflamed joints of patients with RA. MPs were isolated from Jurkat cells and U937 cells by differential centrifugation. SFs were co-cultured with increasing numbers of MPs. The effects of supernatants fro

Additional indexing

Creators (Authors)

  • Reich, N
    affiliation.icon.alt
  • Beyer, C
    affiliation.icon.alt
  • Gelse, K
    affiliation.icon.alt
  • Akhmetshina, A
    affiliation.icon.alt
  • Dees, C
    affiliation.icon.alt
  • Zwerina, J
    affiliation.icon.alt
  • Schett, G
    affiliation.icon.alt
  • Distler, O
    affiliation.icon.alt
  • Distler, J H W
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
15

Number

Number

Number
4

Page range/Item number

Page range/Item number

Page range/Item number
756

Page end

Page end

Page end
762

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2011

Date available

Date available

Date available
2012-01-29

Publisher

Publisher

Publisher
Foundation for Cellular and Molecular Medicine/Blackwell

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
1582-1838

Additional Information

Additional Information

Additional Information
The definitive version is available at www.blackwell-synergy.com

OA Status

OA Status

OA Status
Green

Free Access at

Free Access at

Free Access at
Pubmed ID

PubMed ID

PubMed ID

PubMed ID

Citations

Citation copied

Reich, N., Beyer, C., Gelse, K., Akhmetshina, A., Dees, C., Zwerina, J., Schett, G., Distler, O., & Distler, J. H. W. (2011). Microparticles stimulate angiogenesis by inducing ELR(+) CXC-chemokines in synovial fibroblasts. Journal of Cellular and Molecular Medicine, 15(4), 756–762. https://doi.org/10.1111/j.1582-4934.2010.01051.x

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