Publication: Human muscle precursor cells overexpressing PGC-1α enhance early skeletal muscle tissue formation
Date
Date
Date
2017
Journal Article
Published version
Abstract
Abstract
Abstract
Muscle precursor cells (MPCs) are activated satellite cells capable of muscle fiber reconstruction. Therefore, autologous MPC transplantation is envisioned for the treatment of muscle diseases. However, the density of MPCs, as well as their proliferation and differentiation potential gradually decline with age. The goal of this research was to genetically modify human MPCs (hMPCs) to overexpress the peroxisome proliferator-activated receptor gamma coactivator (PGC-1α), a key regulator of exercise-mediated adaptation, and thereby to en
Additional indexing
Creators (Authors)
- Haralampieva, Deana
- Salemi, Souzan
- Dinulovic, Ivana
- Sulser, Tullio
- Ametamey, Simon M
- Handschin, Christoph
- Eberli, Daniel
Volume
Volume
Volume
26
Number
Number
Number
6
Page range/Item number
Page range/Item number
Page range/Item number
1103
Page end
Page end
Page end
1114
Item Type
Item Type
Item Type
Journal Article
In collections
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Keywords
Cell Biology, Transplantation, Biomedical Engineering
Language
Language
Language
English
Publication date
Publication date
Publication date
2017-02-03
Date available
Date available
Date available
2017-02-17
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
0963-6897
OA Status
OA Status
OA Status
Gold
Free Access at
Free Access at
Free Access at
Pubmed ID
Publisher DOI
Gold Open Access
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