Publication: Three versus six weeks of antibiotic therapy for diabetic foot osteomyelitis: A prospective, randomized, non-inferiority pilot trial
Three versus six weeks of antibiotic therapy for diabetic foot osteomyelitis: A prospective, randomized, non-inferiority pilot trial
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Gariani, K., Pham, T.-T., Kressmann, B., Jornayvaz, F. R., Gastaldi, G., Stafylakis, D., Philippe, J., Lipsky, B. A., & Uçkay, İ. (2021). Three versus six weeks of antibiotic therapy for diabetic foot osteomyelitis: A prospective, randomized, non-inferiority pilot trial. Clinical Infectious Diseases, 73(7), e1539–e1545. https://doi.org/10.1093/cid/ciaa1758
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BACKGROUND
In patients with diabetic foot osteomyelitis (DFO) who underwent surgical debridement, we investigated whether a short (3 weeks), compared with a long (6 weeks) duration of systemic antibiotic treatment is associated with non-inferior results for clinical remission and adverse events (AE).
METHODS
In this prospective, randomized, non-inferiority, pilot trial, we randomized (allocation 1:1), patients with DFO after surgical debridement to either a 3-week or a 6-week course of antibiotic therapy. The minimal duration of fo
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Gariani, K., Pham, T.-T., Kressmann, B., Jornayvaz, F. R., Gastaldi, G., Stafylakis, D., Philippe, J., Lipsky, B. A., & Uçkay, İ. (2021). Three versus six weeks of antibiotic therapy for diabetic foot osteomyelitis: A prospective, randomized, non-inferiority pilot trial. Clinical Infectious Diseases, 73(7), e1539–e1545. https://doi.org/10.1093/cid/ciaa1758
